No long haul symptoms if you start the drug ASAP after first symptoms. Doctors who have used fluvoxamine in the US and other countries swear by it. More recently, hes adopted extremist positions on covid vaccines, which he alleges are toxic. He has claimed that one in 1,000 people who have received mRNA vaccines have died as a result, and even claimed the vaccines kill more people than they save at an FDA public forum, which was first reported by the Daily Beast. ICER: A few months ago, Kirsch suddenly stopped promoting hydroxychloroquineeven scrubbing it from the CETFs official list of trials it has funded. Zero. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. Indeed, some of the most prominent people spreading misinformation about ivermectin and vaccines today began by promoting hydroxychloroquineincluding by claiming to debunk Boulwares data analysis. Im sorry to sound so cynical. 19 In addition, several . Kirsch, despite having direct access to the actual trial runner, eventually became convinced a correct interpretation of the data would show that hydroxychloroquine worked. It is very important to educate doctors because most people rely on their doctors for advice. This advice is now outdated. Steve is a Silicon Valley entrepreneur and philanthropist who founded the COVID-19 Early Treatment Fund (CETF) at the beginning of the pandemic. There are at least eight mechanisms of action that we think contribute to the effectiveness of this drug. No long haul symptoms if you start the drug ASAP after first symptoms. Every year, we pick the 10 technologies that matter the most right now. . Some people report mild nausea while on the drug (stops when stop the drug). To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here.. In-patient use. Steven Todd Kirsch is an American entrepreneur. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. CETF founder Steve Kirsch accepted an invitation to discuss the findings on a weekly . It cant be more clear than this. Reason is the hospital gets release from liability if they follow NIH guidelines. He immediately tweeted an offer to give anyone $1 million if they could win a debate with him about vaccine deaths. In three phone conversations, as well as dozens of emails, his responses to questions about claims in this story were imprecise or constantly changing. The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. Telling the truth, he tweeted. Fluoxetine is just as effective. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. Since making a fortune as the founder of Infoseek, an early search engine that was the Google of its day, Kirsch has spent tens of millions of dollars fighting humanitys biggest threats. The Lancet paper showed that if you were treated early enough and took the drug as prescribed (it only works if you take it), it was shown to reduce your chance of death by 12X making it far more effective than any other drug for COVID. It used to be that a Phase 3 study would do it. He was recently featured on 60 Minutes, . The Lancet paper showed that if you were treated early enough and took the drug as prescribed (it only works if you take it), it was shown to reduce your chance of death by 12X making it far more effective than any other drug for COVID. MD, MPH; Steven C. Marcus, PhD. The drug was widely prescribed as a covid treatment for much of 2020, based on anecdotes and flawed studies. Ivermectin and fluvoxamine have been confirmed in Phase 3 trials. We pretty much practice government agency opinion medicine all over the world now, with just a few exceptions. The paramedics will think you are on drugs. There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. An approach that promised to democratize design may have done the opposite. Hilary Grant-Valdez Operations Manager Tom Brunner That was a big mistake because the original paper contained text related to earlier studies and the editors chopped it out. Author Affiliations . 1:49 Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. The NIH wrote a bullshit rejection because the FDA told them not to approve it. This story is part of the Pandemic Technology Project, supported by The Rockefeller Foundation. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 1.15K 'This Has Cost Millions of Lives': Steve Kirsch on Suppression of Repurposed Drugs and a Spike in Deaths 5 Months After Vaccine Rollout American Thought Leaders AMERICAN THOUGHT LEADERS JAN JEKIELEK Show more Loading comments. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. My experience is very typical. I will . The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. But how many did it help? Your best bet is to. Online. Enter the email address you signed up with and we'll email you a reset link. The FDA approved Molnupiravir which was less effective. The data is there in plain sight for anyone to see today. Kirsch did a lot of things right when he set up CETF. more time. We should not wait for the Phase 3 RCT. They left their recommendation of fluvoxamine at NEUTRAL. . Steve Kirsch's Newsletter ^ | 02/26/22 | Steve Kirsch. Always be self aware when using fluvoxamine. In the second trial, it was shown to be 100% effective in long-haul COVID symptoms: None of the treated patients had any long-haul symptoms after 2 weeks compared to 60% of untreated patients having 1 or more of the 15 long-haul symptoms after two weeks, and 29% having 4 of more of the long haul symptoms after 2 weeks. If you start 5 days after symptoms, all bets are off. Fluoxetine is just as effective. Why not fluvoxamine? So it was both obvious and convincing the difference between the groups to the workers and the track management. Thats what creates some of these heroes.. Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. During our first conversation, which turned into a multi-hour Zoom session, Kirsch paced through the rooms of his cavernous house with his phone held at chest level, rarely looking down at the camera. Dosage there is 30mg once a day. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. Have the drug on hand. So much for evidence-based medicine. Steve Kirsch said scientists and clinicians are studying a host of drugs and therapeutics to create a new line of defence against the virus but clinical trials are yet to lead to conclusive. Hes a genuinely good guy. He retired at the largest pension in federal history. After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. But while this effort was praiseworthy, Kirsch's predilection for oversimplifying and exaggerating led him to mislead. You cannot get any better than that. And, according to three members of CETFs scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for covid. 90,000 people don't have to die in the next 3 weeks. . Several other trials around the world are in the final stages, too. Dr. Seftel is an NIH-funded researcher and an NIH reviewer. In May, all 12 members of CETFs scientific advisory board resigned, citing his alarming dangerous claims and erratic behavior. Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. sorry about that. While these are stunning results, less than a dozen doctors in the US are prescribing fluvoxamine today. Their willingness to lie did. In two trials (both published studies in peer reviewed journals with Editor's Choice in both cases), the drug had a 100% effect size in protecting against hospitalization from the respiratory symptoms from COVID. Long haul. But not 150K. When I asked him why so many experts in the field disagreed with him, he alleged there were effortseither malicious or negligentto suppress evidence of cheap, effective covid treatments. The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! Doctors have no excuse for not prescribing. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. There are 4 outpatient studies that have been done (2 at WashU (see. Talking to Kirsch is an exhausting experience. Today, if we follow the CDC advice, nearly 100,000 people a month will die from COVID. Most recent articles first. The trials that were abandoned for futility werent getting events because the patients were given standard of care meds. I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. Over the summer, the conflict reached his most recent startup, M10. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. Fauci wants the vaccine to be the only option, Cliff Lane works for Fauci, and Cliff follows his orders. I mean, he really, truly has a heart of gold, Char told me. If you take fluvoxamine, please avoid caffeine while on the drug. It has enrolled only 130 people in the first month and is enrolling only 70 per week now. While YouTube has repeatedly taken down the full video of the DarkHorse episode, various clips have been watched over 4 million times, and the full audio remains available on Spotify. I couldnt tell I was on the drug. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. Hes spending his own money to do what he thinks is right. Thats why they didnt even fund the fluvoxamine trial, he told me. Doctors who have used fluvoxamine in the US and other countries swear by it. Kirsch, though, often relies on the heartstrings to smooth over a lack of data. Less than a week later, David Seftel read about the Lenze trial, and ignored the JAMA advice. [https://www.quora.com/What-is-the-current-treatment-for-Covid-19/answer/, The most urgent need in the country right now is to reduce. Who knows, Morris replied. . As Kirsch has gone deeper into the anti-vaccine scene, many professional associates have increasingly distanced themselves from him. This drug can save your life but you have to ask for it! 90,000 Americans will die from COVID in just the next 3 weeks, a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die, Lenze fluvoxamine RCT that was published in JAMA. If you cant lay off the java, then try fluoxetine (Prozac). just like ivermectin). By the beginning of September, he was no longer the companys CEO, replaced by his co-founder, Marten Nelson. Timing is everything with respect to outcomes. That is when the phase 2 results were published. Compulsive hand washing? Saving the world has been a theme of Kirschs life for years. Here is what, e) which concluded: Under a variety of assumptions, fluvoxamine shows a high probability of preventing hospitalization in outpatients with COVID-19., For more about fluvoxamine (and other SSRIs that work), see, fluvoxamine completed a Phase 3 study showing it works that was published in the Lancet Global Health, NIH basically dismissed the fluvoxamine study as I predicted they would, few people werent afraid of expressing their displeasure, the highly acclaimed Bangladesh mask study showed, Johns Hopkins has incorporated fluvoxamine in their treatment guidelines, Ontario has become the first province to list fluvoxamine as a treatment doctors can consider for patients. Timing is everything with respect to outcomes. My favorite dosage is 50mg twice a day for 14 days. That work has yielded one promising candidate, the antidepressant fluvoxamine; other CETF-funded efforts have been less successful. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. The sooner you start, the better the outcomes. My crime? 33. The babys brain was split in half, and it was just covered with blood. Although there is evidence that fluvoxamine can prevent clinical worsening and the need for hospitalizations in outpatients with early covid-19, I have seen no good evidence that fluvoxamine is useful as a substitute for the vaccines, co-investigator Angela Reiersen wrote to me. skirsch.io Steve Kirsch Home page. Both of them encouraged anyone reading this article to get vaccinated. including the very promising Fluvoxamine. Medium banned him for misinformation. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! Sage Hana. Try refreshing this page and updating them one ICER Publishes Final Evidence Report and Policy Recommendations on Outpatient Treatments for COVID-19 - ICER. Another is to identify an asteroid that is going to hit the planet.. By Steve Kirsch Mar 14, 2021 Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for a single drug to be 100% successful. (Siliciano did not respond to requests for comment for this article.). Dr. Joe Ladapo wrote a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients." 1 hr ago. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. O, Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19 | Blood Advances | American Society of Hematology, Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008, Fluvoxamine for COVID-19 Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008, Drug Repurposing Research Leads to Potentially Game-Changing Treatment to Prevent Clinical Deterioration in Outpatients With COVID, The Covid-19 Early Treatment Fund was launched to provide funding for research in order to, Steve Kirschs answer to What is the current treatment for Covid-19? If you continue to get this message, Server IP cope with resolved: Yes Http reaction code: 200 Response time: 0.27 sec. Those who know Kirsch say this is a typical tactic. iRobot said it had consent to collect this kind of data from inside homesbut participants say otherwise. Thats pretty typical, but your mileage may vary. At that dose, no side effects were reported for his patients (I know of only one person who had mild nausea at that dose) and everyone reversed out their symptoms in an average of 3 days. So it was both obvious and convincing the difference between the groups to the workers and the track management. For decades, coders wrote critical systems in C and C++. Waiting months for the phase 3 trial to complete is nuts. With little government funding available for such work, Kirsch founded the Covid-19 Early Treatment Fund (CETF), putting in $1 million of his own money and bringing in donations from Silicon Valley luminaries: the CETF website lists the foundations of Marc Benioff and Elon Musk as donors. Twenty-four years ago, . It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. Online Status. Ivermectin has a very high quality systematic review, the highest possible level in Evidence Based Medicine. I asked to give a talk about COVID at MIT, but they couldn't find a faculty member to sponsor it. Please, As of November 13, fluvoxamine has been proven to work in every trial that has published results, including, studies. They knew in advance it was coming and on the day the paper was published they ignored it entirely. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. But fear of trying something new prevents any doctor from giving this drug a try. What has alarmed many of the scientists associated with CETF, though, are Kirschs reactions to the work hes fundedboth successes and failures. One Silicon Valley entrepreneur thought he could beat the odds. This site requires JavaScript to run correctly. On Dr. Drew, he told a story about a friends daughter who had to get an abortion because of damage caused by the shot. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. If you cant get a prescription for COVID, then perhaps you have OCD? . There were no studies reported out so far where fluvoxamine made things worse or neutral. The 5 observational studies is icing on the cake. . In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. We dont want to feed the anti-vaccine trolls, so we actively suppress clear scientific data. It has shown to be 100% protective of hospitalization in 2 clinical trials. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital security (OneID), or e-commerce (Propel Software). Fluvoxamine is an inexpensive drug that has been in use for 37 years and has been used by an estimated 10 million people. There is absolutely no evidence that either one of these claims is true, as Morris has carefully documented. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. He has been a medical philanthropist for more than 20 years. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. Note that some of these articles are inaccurate. But even she was drained by Kirschs constant attempts to override the data. So much for evidence-based medicine. At the beginning of the COVID-19 pandemic, Steve Kirsch created the COVID-19 Early Treatment Fund (CETF) to finance trials of off-patent drugs in an attempt to find a potent treatment that had been staring us in the face. They never make things worse so are safe to try. I only know of a few doctors who prescribe this off-label, all with 100% success rates. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. The evidence is solid. Don't underestimate the virus. Fluvoxamine public data repository - Google Drive, On Cytokines, Fluvoxamine and COVID-19 Part 1, Jon-Emile S. Kenny MD[@heart_lung] You see, we have a kind of allergy to the past; its our national disease, and the very assurance with which you insist that the past is within the present is l, On Cytokines, Fluvoxamine and COVID-19 Part 2, Jon-Emile S. Kenny MD[@heart_lung] Apocalypse is played out now on a personal scale; it is not in the sky above us, but in our bed. -Mark Doty Introduction With a proposed pathway coupling patho, Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19, This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reactionconfirmed mild coronavirus disease 2019 (, Prospective cohort of fluvoxamine for early treatment of COVID-19, Abstract. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008 Google Docs This is a more comprehensive look at the key evidence supporting fluvoxamine: Fluvoxamine for COVID-19 Physicians who use the drug for COVID now swear by it. Quick Summary . After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). You will be wired for 24 hours if you dont heed my advice. So why would we wait when lives are being lost? Infoseek lost out to Yahoo; it had a chance to grow bigger, but it didn't. Always be self aware when using fluvoxamine. . This is a more comprehensive look at the key evidence supporting fluvoxamine: Hear from the doctors who did the studies directly as well as the Dean of Medicine at Emory University: List of the best evidence-based COVID treatment options. And that is what has allowed Kirsch, and people like him, to become so influential. The combined p value of the two studies is <.0001. Items included in the Television News search service. One is to reduce the threat of nuclear war. Steve Kirsch, current director of the Covid 19 Early Treatment fund is an MIT alumni who has made a career as a tech entrepreneur. His efforts became more focused on medical research when, in 2007, he was diagnosed with a rare blood cancer. Author Affiliations Article Information. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. , or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). In November, CETF gave the group an additional $500,000 for a phase 3 clinical trial that might show conclusive proof of efficacy. Those days are gone. Fluvoxamine, created 37 years ago, is an inexpensive and widely available generic drug. He might be a good snake oil salesman., I experienced this myself when, on one call, we discussed several studies. . NIH doesnt want you to get the drug since it would compete with Molnupiravir, so fluvoxamine will never make the NIH guidelines. Hes also publicly railed against what he claims is a campaign against drugs like fluvoxamine and ivermectin. Our in-depth reporting reveals whats going on now to prepare you for whats coming next. This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. The post read: "I will be featured on 60 Minutes this Sunday talking about fluvoxamine as an effective treatment for COVID-19 to prevent hospitalization and death. There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. You will be wired for 24 hours if you dont heed my advice. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . I've asked people, "there's a lot of evidence here it's not just a small phase 2 RCT. In short, a lot of mumbo jumbo. If you start 5 days after symptoms, all bets are off. Get your prescription in advance of getting COVID. All the researchers are convinced the drug works. Fluvoxamine was reportedly added to just 2 practice guidelines (. He has made millions from these projects, even if they have not turned him into a household name. Its the gold standard of medical evidence. He started a new pseudonymous account, @VaccineTruth2, to continue broadcasting messages. That trial has now been completed, and the researchers are analyzing their data. That was a lie. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. 533. None of this would really matter if Kirschs views on vaccinations were private, or shared with a limited audience. The Wall Street Journal thinks it should be used (and that the NIH is wrong for waiting for more clinical trials). He applied the drug to a large COVID outbreak at Golden Gate Fields just days after the Lenze trial was published. It should be crystal clear to everyone that the current CDC guidelines for treating COVID aren't working. As trial results rolled in, that mismatch began to put a strain on Kirschs relationship with the funds advisory board. Then he hosted a superspreader event. They knew in advance it was coming and on the day the paper was published they ignored it entirely. Thirty minutes past the end of our scheduled time, he dropped his phone in the cupholder of his Tesla so that he could keep talking while he ran an errand. So the drug had no chance of working (since there were no events), so the trial was stopped for futility, NOT because the drug doesnt work. The track management was so impressed, they asked for prescriptions. Comparison with molnupiravir. Its a cycle that feeds mistrust and boosts the profiles of influencers who present themselves in opposition to official authorities. As of January 18, 2021, the CDC estimates that 90,000 Americans will die from COVID in just the next 3 weeks. Early treatment with existing drugs is the fastest, most effective, and lowest. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. See this Wall Street Journal op-ed. I fully expected both organizations to do absolutely nothing. But the potential upsides. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to. May 16, 2022. Has it really been 25 years, a whole quarter of a century? A very short op-ed arguing for using fluvoxamine against COVID. He told me that while he and his family got vaccinated as soon as they were eligible, he got the idea that vaccines are dangerous from a man he hired to clean his carpets, who got very sick after receiving the vaccine. 1. Seftel was able to duplicate the 100% protection from hospitalization and death in the treatment group, vs. a 12.5% hospitalization/death rate for the No treatment group. The drug was FDA-approved more than 65 years ago. this is NOT about the science. One user reported dilated pupils and increased heart rate (which could be nerves about the dilated pupils). Added to FLCCC protocols and Fareed-Tyson protocol among others. Early research suggests that fluvoxamine, an FDA approved medication for depression and obsessive compulsive disorder, can be an effective early treatment for COVID-19. They immediately ruled out the vaccine, because the vaccine is, quote, safe.. We could have saved a lot of lives. The premise made sense: Most experts were predicting vaccines would take years, while finding helpful drugs with known safety profiles could shortcut the approval process. If you start later, doctors use higher dosages and compliance becomes a bigger problem. Im not going to make the same mistake again.. Online. upcoming events, and more. The reason that it isnt used is because the medical community ignores evidence-based medicine principles. . Reason is the hospital gets release from liability if they follow NIH guidelines. Last Checked: 03/02/2023. Steve Kirsch reported that doctors commonly say (of fluvoxamine), "This is the most powerful drug in my arsenal. That covers almost 150,000 of them, which happened before vaccinations began.