(adsbygoogle = window.adsbygoogle || []).push({}); A drug screen tests for the presence of certain illegal drugs and commonly misused prescription medications. Can Certain Foods, Drinks, And Meds Cause A . My recommendation to anyone taking these medicines who might be drug tested is first and foremost to be honest with the tester, says Dr. McFadden. You could have a false-positive result if blood or protein is present in your urine. Prescription methamphetamine (Desoxyn) is composed entirely of the d isomer. Common over-the-counter anti-inflammatory pain medications such as. Medications that have been reported to cause false-positive results for methamphetamine or amphetamine include: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Several common prescriptions, over-the-counter medications, herbs, vitamins, and even some foods could trigger a false positive drug test. Due to the potential for cross-reactivity associated with immunoassay urine drug screens, several prescription and non-prescription drugs have been reported to cause false-positive results.2,6 In addition to medications, several other substances have been associated with false-positives, such as baby wash products, supplements, and food. The d,l-isomer test also is performed by MS. Understanding each of the 3 testing steps is essential to clinical decision making related to patient care. Taking Sudafed can result in a false positive for amphetamine or methamphetamine. A key ingredient in Sudafed (pseudoephedrine) is also the main ingredient to the making of methamphetamine. eCollection 2022. According to research, its highly unlikely that secondhand smoke will cause a false positive test for marijuana. used to treat hypertension and chest pain, may result in false positive drug test results for. It is a common misconception that alcohol can cause a negative pregnancy test. In addition to prescription medications, these other common substances can lead to a false positive drug test. Common Vitamins Supplements can cause a false positive test. Methamphetamine produces subjective effects that are similar to those of cocaine, and it is for this reason that it is often a medication of abuse.In 2011, 133,000 persons aged 12 years or older abused methamphetamine for the first time and the overall number of past-month methamphetamine abusers was 439,000.Methamphetamine abuse carries significant morbidity. 2021 Oct 27;13(10):e19082. [PMID 23088194] Follow me on Twitter . Limit your exposure to toxins and do not spend time in toxic environments. Drug concentration level thresholds are used in reporting of positive and negative reports for urine drug testing.2 If a test detects a concentration above the threshold, it is reported as positive, and vice versa for negative results. In addition a number of other medications and their metabolites can also cause false positive result for Methamphetamines they include; Metformin: Metformin (Glucophage) is the most commonly prescribed oral medication for diabetes. Promethazine. is a drug commonly used to reduce the blood sugar of diabetic patients. 13. New DOT Drug Testing Cutoff Levels 2021/2022. If it is prescribed, make sure you have the label from the pharmacy, which will show that the medication was prescribed to you. Comprehensive Psychiatry, 94, 152126. https://doi.org/10.1016/j.comppsych.2019.152126. It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. What causes a false positive? , including the frequency of drug use and the how fast the drug is metabolized by the body. Using current methodology for urine toxicology testing will allow clinicians to narrow down the possible source of a positive result and assist them in managing their patients accordingly. Additionally, a thorough medication history should be obtained to anticipate false-positive results. False-negatives and false-positives from immunoassays can lead to adverse consequences for patients and providers. DMAA (1,3-dimethylamylamine), found in some dietary and weight-loss supplements. In the United States, methamphetamine is a schedule II drug and is approved for treating both attention deficit hyperactivity disorder and obesity under the brand name Desoxyn. Taking metformin may result in a positive test for amphetamine or methamphetamine. Then there's . Labetalol can also cause a false positive for amphetamine or methamphetamine because a labetalol metabolite is structurally similar to amphetamine. In one study, 49 out of 50 patients taking the drug tested positive for benzodiazepines. Liquid chromatography/tandem mass spectrometry (LC-MS/MS) is an alternative to GC-MS and may be more time efficient. This information is intended as an educational piece and should not be used as the sole source for clinical decision making. The information presented is current as April 5, 2021. A false positive is when a drug test shows the presence of a medication or substance that you didn't actually take. Drug testing can be performed using various biologic specimens, including urine, saliva, hair, sweat, nails, meconium, and blood. Urine drug screening: a valuable office procedure. According to one, , false positive drug tests are most commonly reported for amphetamine and methamphetamine. This might look like someone used illegal drugs (such as methamphetamines or opiates) when they did not. Learn how we can help. Many medicines you can purchase at your local chemist containing pseudo-ephedrine, ephedrine, or other sympathomimetic amines tend to interfere with urine screening tests and cause false positive results for amphetamines, but do not cause positive test results in the gas chromatography/mass spectrometric, or GC/MS, confirmation, thus pose no . To quote a study published in the Journal of Clinical Biochemistry, " commonly used soap and wash products used for newborn and infant care as potential causes of false positive THC screening results .". Promethazine is part of a group of medications called phenothiazines. Methamphetamine Intoxication and Perioperative Complications Following Orthopaedic Surgical Procedures. 1-3 It was prescribed to the patient for symptomatic treatment of irritable bowel syndrome. Its important to note that no drug test is 100% accurate. Prilosec (omeprazole), Nexium (esomeprazole), and Prevacid (lansoprazole) are used to treat gastroesophageal reflux disease (GERD) or peptic ulcer disease (PUD) and can cause a false positive for THC. Accessed April 8, 2021. An otherwise healthy 27-year-old female with a history of attention deficit hyperactivity disorder (ADHD) treated with atomoxetine had an acute onset tonic-clonic seizure. There are many different over the counter and prescription medications that have been reported to cause false positives for methamphetamine on a drug test. Accessed October 4, 2012. RELATED: Benadryl details | Doxylamine details. Epub 2015 Nov 2. - Some legal over-the-counter drugs (such as Vicks VapoInhaler ) and some foods (such as poppy seeds) may cause a positive screening drug test. If you're a fan of Seinfeld, then you already know that poppy seeds can cause a false positive at a drug screening. Quinolone antibiotics: Quinolone antibiotics such as levofloxacin (Levid 500), ofloxacin and ciprofloxacin are commonly prescribed for urinary tract infections, pneumonia, and sinus infections among other things. Amphetamine. Categories of medications included antihistamines, antidepressants, antibiotics, analgesics, antipsychotics, and nonprescription agents. Besides prescription sources, methamphetamine (ie, crystal meth) can also be produced in small, clandestine laboratories using ephedrine or pseudoephedrine as a key ingredient. We recommend using the latest version of IE11, Edge, Chrome, Firefox or Safari. False-positive results can be due to a laboratory error, but the most common reason for a false-positive methamphetamine test is other medications or substances that have a similar structure to methamphetamine. Nationwide Testing Association Inc. https://ntatesting.com/did-a-vicks-inhaler-cause-my-positive-test/. Bethesda, MD 20894, Web Policies What over the counter and prescription medicine show a false positive on methamphetamine tests? 5-7 Non-amphetamine prescription, illicit, or over-the-counter . Mandatory guidelines for federal workplace drug testing programs. In general passive inhalation of crack cocaine does not cause a false-positive; however, it has been reported in cases of chronic exposure. Both d and l forms test positive by both immunoassay and most confirmation assays. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Metformin. The l form is available over-the-counter as the active ingredient of a specific Vicks inhaler and is a metabolite of certain prescription medications. They both use similar principles. 12. Taking Sudafed can result in a false positive for amphetamine or methamphetamine. Although the affinity of the antibody for these substances is much lower than for fentanyl, if they are present at sufficiently high concentrations, they can cause a false positive result [24, 25]. Please enable JavaScript!Bitte aktiviere JavaScript!S'il vous plat activer JavaScript!Por favor,activa el JavaScript!antiblock.org. https://www.uspharmacist.com/article/urine-drug-screening-minimizing-false-positives-and-false-negatives-to-optimize-patient-care#:~:text=The%20FGAs%20chlorpromazine%2C%20prochlorperazine%2C%20haloperidol,cause%20false%2Dpositive%20LSD%20results.&text=Thioridazine%20may%20additionally%20cause%20false,in%20structure)%20and%20methadone%20results. If, under their physicians approval, the person can be off the medicine for that length of time, a negative test should result.. Unauthorized use of these marks is strictly prohibited. Substance Abuse and Mental Health Services Administration (SAMHSA). Esposito FM, Crumpton S, Mitchell J, Flegel RR. Toxicology. If youre taking labetalol, you could have a false positive test for amphetamine, methamphetamine, or LSD. Research suggests that 10% to 15% of drug tests yield false negative results. A retrospective chart review of 10,011 urine drug screens found that of 362 initial positive amphetamine tests, 128 (35%) were false positives. 2015 Dec;136(6):e1625-8. The most commonly used tests to screen urine for drugs of abuse are immunoassays, even though false-positive results for drugs of abuse have been reported with a number of these rapid-screening products. Know if the meds you are taking might cause a false positive and notify the administrator of the test. Clipboard, Search History, and several other advanced features are temporarily unavailable. There is no definitive research suggesting that other drugs can cause a false positive for gabapentin, aside from Lyrica (pregabalin), a drug closely related to it. The first test is an immunoassay (IA) screening test for the amphetamine class of medications, which includes both amphetamines and methamphetamines. Dextromethorphan, the active ingredient in Robitussin-DM, Delsym, and other over-the-counter cough suppressants, may cause a drug screen to be positive for opiates and/or PCP. Unable to load your collection due to an error, Unable to load your delegates due to an error. UIC's seven health sciences colleges and health care delivery enterprise. Brahm NC, Yeager LL, Fox MD, Farmer KC, Palmer TA. Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2009: National Estimates of Drug-Related Emergency Department Visits. January 23, 2017. Hopefully I've answered your questions satisfactorily. A false positive means that the test has detected the presence of these substances in your body when you havent actually taken them. Although this is not a high percentage, the consequences for failing a drug test could jeopardize your career, education, or job prospects. False-positive results Certain medications, foods, and disease states may cause valid outliers; however, a pH <3 or >11 or a specific gravity <1.002 or >1.030 increases the suspicion for adulteration. If, under their physicians approval, the person can be off the medicine for that length of time, a negative test should result.. Avoid everything that could cause a problem and result in another false positive for amphetamines. This test is more specific than immunoassay testing, as it detects drugs by molecular structure. Brunton L, Blumenthal D, Buxton I, Parker K. Substance Abuse and Mental Health Services Administration. Methamphetamine Information for Consumers, Methamphetamine Information for Healthcare Professionals, DMAA (1,3-dimethylamylamine), found in some dietary and weight-loss supplements, DeGeorge, Jr. M, Weber J. Methamphetamine Urine Toxicology: An In-depth Review. Medically reviewed by Carmen Fookes, BPharm. medications can result in false positives for these substances. The temperature of urine should be between 90 to 100 degrees Fahrenheit measured within 4 minutes of collection; the pH should be consistent with the range of 4.5 to 8; the specific gravity should be between 1.002 and 1.030; and the creatinine should be greater than 20 mg/dL. The next thing that may cause a false positive on a drug test is a vitamin B supplement . Pseudoephedrine. 10 Kinetics Interaction of Microparticles in Solution (KIMS, Roche), a monoclonal antibody assay, identified possible false-positive results for chlorpromazine, clomipramine, and thioridazine. , and other over-the-counter cough suppressants, may cause a drug screen to be positive for opiates and/or PCP. When a specified drug is present in a test urine sample, an antibody binds to it and produces a reaction. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Amphetamines are central nervous system stimulants that cause a reaction of of amphetamine-containing drugs . What Can Cause A False Positive For Methamphetamines, List Of Worst Foods and Drinks For Brain Health, The Benefits of Mindfulness: Sherief Abu-Moustafa Shares How To Incorporate it Into Your Life, How to Get a Medical Marijuana Card in California, How Your Blood Group Increases Your Risk Of Developing Some Diseases, WHO sends health supplies to reach 400 000 people impacted by the earthquakes in Trkiye and the Syrian Arab Republic, Longstanding WHO partners to enter into official relations with the Organization, WHO launches new roadmap on breast cancer, Celebrating World NTD day with a photo exhibit: Reframing Neglect. Research conducted at Boston Medical Center shows that drug tests produce false positives in 5% to 10% of cases. So, if you are like most people who dont take the time to study the fine print, here is a list of prescriptions and over-the-counter medications that could cause a false positive drug test. If no amphetamines are detected, then the amphetamine result is negative and no further testing is needed. Case reports in psychiatry, 2013, 381261. https://doi.org/10.1155/2013/381261, Merigian, K. S., & Browning, R. G. (1993). Thats because common over-the-counter medications can result in false positives for these substances. If you get a false positive for methamphetamine, you could simply ask to retake the test if that is allowed. Immunoassay technology uses antibodies to detect drug metabolites. If the specimen contains more than 20% d-methamphetamine, then the donor is to be considered positive for illicit methamphetamine use. HHS Vulnerability Disclosure, Help A false positive result occurs when the analytical drug detection method recognizes some of the molecules in the body as illegal drugs when you havent ingested any illegal substances. Labetalol: Labetalol (Trandate) is both an alpha- and beta-blocker drug used for blood pressure control. https://www.cdc.gov/nchs/fastats/drug-use-illicit.htm, https://www.samhsa.gov/workplace/resources, https://www.samhsa.gov/sites/default/files/workplace/2010GuidelinesAnalytesCutoffs.pdf, https://www.federalregister.gov/documents/2017/01/23/2017-00979/mandatory-guidelines-for-federal-workplace-drug-testing-programs, https://accesspharmacy.mhmedical.com/content.aspx?sectionid=210267566&bookid=2569#216818178, Amantadine, aripiprazole, atomoxetine, brompheniramine, bupropion, chlorpromazine, desipramine, DMAA, ephedrine, fluoxetine, labetalol, metformin, ofloxacin, phentermine, phenylephrine, phenylpropanolamine, promethazine, pseudoephedrine, ranitidine, selegiline, thioridazine, trazodone, nonprescription nasal antihistamine/decongestant inhalation, Baby wash products, dronabinol, efavirenz, ibuprofen, lamotrigine (on screenings for synthetic cannabinoids), naproxen, niflumic acid, proton pump inhibitors, Ambroxol, amitriptyline, benzphetamine, bupropion, buspirone, cephradine, chlorpromazine, desipramine, diltiazem, doxepin, fentanyl, fluoxetine, haloperidol, imipramine, labetalol, metoclopramide, prochlorperazine, risperidone, sertraline, thioridazine, trazadone, verapamil, ergonovine, lysergol, brompheniramine, imipramine, methylphenidate, fentanyl, sertraline, Diphenhydramine, doxylamine, chlorpromazine, clomipramine, doxylamine, quetiapine, thioridazine, verapamil, Amisulpride and sulpride, codeine, dextromethorphan, diphenhydramine, dihydrocodeine, morphine, methadone, morphine-3-glucuronide, creatinine, dihydrocodeine, levofloxacine, ofloxacine, morphine, naloxone, ofloxacin, petanzocine, psychotropic drugs, quetiapine, rifampicin, tapentadol, tramadol, verapamil, quinolones, quinine, Dextromethorphan, diphenhydramine, doxylamine, ibuprofen, imipramine, ketamine, lamotrigine, MDPV, meperidine, thioridazine, tramadol, venlafaxine. The Adderall will show up as a false positive for Methamphetamines. 2016;41 (8):26-30. J Am Coll Emerg Physicians Open. Ofloxacin has also been shown to cause a false positive test for amphetamine or methamphetamine. False-positive results Due to the potential for cross-reactivity associated with immunoassay urine drug screens, several prescription and non-prescription drugs have been reported to cause false-positive results. Tim Thoelecke, CSAPA, is the founder of InOut Labs. Similarly, Zoloft (sertraline) may show up as a benzodiazepine. (the active ingredient in Unisom) can also trigger a positive drug result for methadone, opiates, and PCP. Several medications can produce a false-positive result for methadone on the urine drug screen: diphenhydramine, doxylamine, clomipramine, chlorpromazine, quetiapine, thioridazine, and verapamil. Gas chromatography/mass spectrometry (GC-MS) is the gold standard for confirmatory testing. Urine drug testing is frequently performed by immunoassay (IA) due to ease of use, rapid turn-around time and the ability to screen multiple drug classes. doi: 10.1002/emp2.12702. Used as an antidepressant, for weight loss, and smoking . All of the following medications have documented cases of causing a false positive for either amphetamine or methamphetamine: Amantadine. Last updated on Aug 18, 2022. Murray EP, Mansy L, Lackey JT, Link RC, Bonanni S, Sorensen AA. Epub 2014 Jul 1. He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! The commonly prescribed antidepressant, trazodone, has been reported to cause false positives in 3,4-methylenedioxymethamphetamine (MDMA) UDSs. The pain medication, . Created for people with ongoing healthcare needs but benefits everyone. Researchers are studying how the body handles chemicals that may test . FOIA A false-positive test result means that your drug test shows the presence of a medication or substance that you aren't actually taking. Based on a 1991 Department of Health and Human Services Technical Advisory, a d-methamphetamine level that is >20% of the total is considered indicative of a source other than an OTC product or a metabolite of selegiline. These sources could include a prescription medication or illegally manufactured methamphetamine. Desoxyn [package insert]. My recommendation to anyone taking these medicines who might be drug tested is first and foremost to be honest with the tester, says Dr. McFadden. doi: 10.1542/peds.2014-3333. Can Albuterol Cause a False Positive Drug Test? 11 /11. , and are well known to cause a false positive for amphetamines and methamphetamines. Various immunoassay drug tests are available on the market, and each test uses a proprietary antibody technology, leading to differences in false-positive results between tests.7 Furthermore, immunoassays may be reformulated to correct for false-positive, which may not be adequately reflected in published literature. suggests that 10% to 15% of drug tests yield false negative results. Prescription methamphetamine (Desoxyn) is composed entirely of the d isomer. Antihistamines and some sleep aids containing diphenhydramine (like Benadryl) could cause a false positive result for PCP or methadone. Among its few physiological effects is vasoconstriction, which makes it useful for nasal decongestion.. Accessed October 9, 2012. Many positive phencyclidine (PCP) tests are due to cross-reactivity; given that it is no longer commonly abused in the U.S., with the exception of select regions, clinical presentation should be used to guide management without the use of an immunoassay drug screen.6 Immunoassays for tetrahydrocannabinol (THC) are not able to detect newer synthetic cannabinoids. With CBD available in everything from drink powders, to weight loss formulations, to tinctures of all types, false positive urine screenings for THC will become more and more common, warns Dr. McFadden. official website and that any information you provide is encrypted Mayo Clin Proc. Many drug abusers will make the commitment to stop, and you therefore need an accurate test to verify and confirm this. These prescriptionsand other substancescan skew the results of a screen for illicit substances, Find out if caffeine interacts with these prescriptions for hypertension and heart problems. Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. Illicit methamphetamine availability and use poses a serious health risk in the United States today. She took the medicine twice a day (at 8 am and 8 pm), and the last dose was administered 9 hours before ED access. False positives on drug tests are unfortunately fairly common. When consumed in large quantities (such as in a poppy seed bagel or muffin), the tiny black seeds might cause a false positive drug result for opioids. Sertraline (Zoloft) Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of . Accessed April 8, 2021. The main issue is the tests themselves. What Does A Faint Line On A Drug Test Mean? https://www.practicalpainmanagement.com/treatments/pharmacological/non-opioids/methamphetamine-urine-toxicology-depth-review, Did A Vicks Inhaler Cause My Positive Test? 2022 Mar 17;3(2):e12702. that you have taken it., Riboflavin, also known as B2, is found in hemp seed oil and may return a. is the non-psychoactive portion of the marijuana plant that has become a very popular remedy for everything from pain control, to promoting sleep, to helping relieve anxiety. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Pseudoephedrine is a decongestant that is commonly used to treat nasal congestion and sinus infections. For this reason, immunoassay testing should be considered preliminary and presumptive. yes it will show as a false positive in the drug screen urine test. Urine is most commonly used due to its ease of collection. Off-label Use of Pain Treatment No Longer Covered by Insurance, Musculoskeletal Ultrasound: A Primer for Primary Care, The Next Barriers to Care: Your Local Pharmacy, Why Podiatric Medicine Must Embrace Pain Management. I would counsel [anyone who received a false-positive test to ask] the administrator to do a more specific test, says Dr. McFadden, who recommends samples be sent away to labs to have a more specific mass spectroscopy assay done. , its highly unlikely that secondhand smoke will cause a false positive test for marijuana. eCollection 2021 Oct. False-positive interferences of common urine drug screen immunoassays: a review. Drug tests are also performed in the workplace to identify illicit substance abuse. November 25, 2008. What Can Cause A False Positive For Methamphetamines? Confirmatory testing should be considered following a presumptive positive screening test.2 The decision to perform a confirmatory test should take into consideration the patients history, clinical judgement, and the potential impact on patient care. 2023 SingleCare Administrators. False Positive Tramadol Urine Testing in Patients Taking Fexofenadine: A Tale of Two Consecutive Cases. Positive results on urine immunoassay screening should be considered presumptive, and confirmatory testing with GC-MS should be considered to confirm the findings. drbrush, Board Certified Physician. Alcohol in hand sanitizer (from heavy use), certain liquid medications, and mouthwash or other breath cleaning products could cause you to test positive for drinking alcohol. eCollection 2021. False positive for Methamphetamines is quite common because some amphetamine (AMP) and Methamphetamine urine immunoassay (IA) kits are prone to false-positive results due to poor specificity of the antibody according to a study published in the Journal of Analytical toxicology. If it is an OTC product, have some kind of documentation (the container it was in, a note from your physician, etc.) The immunoassays can cross-react with commonly used medications or its metabolites and show a false positive level for substances that are banned by an employer. My question Im in pain mgmt and I take norco as needed everyday. These tests are only 95% accurate. 3. 1. Abuse and misuse of prescription and illicit drugs is a growing concern, with 11.7% of the U.S. population over 12 years of age reporting illicit drug use in 2018, an increase from 7.9% in 2004.1,2 Drug testing is frequently used in clinical setings to identify substance-use disorders, confirm medication adherence, or identify overdoses. , may produce a false positive drug test. A poppy seed can lead to a false-positive test result because it contains naturally occurring compounds also present in morphine and codeine. However, IA drug screens have limited sensitivity and specificity due in part to capture antibody cross-reactivity with structurally similar interfering compounds, producing false-positive results. Nelson ZJ, Stellpflug SJ, Engebretsen KM. Can OTC and prescription drugs affect a pregnancy test? This has prompted restrictions on the distribution of these over-the-counter (OTC) medications. Updated: 6:28 PM MDT May 25, 2016. When a reaction occurs, it is classified as 'positive' result. Summary: While urine drug screening using immunoassay is convenient, the test is associated with multiple limitations. An understanding of these limitations is necessary to identify false-positive and false-negative results. The DHHS cutoff values were developed for adults, and lower thresholds should be used for infants. In our latest question and answer, the pharmacist discusses what over the counter and prescription drugs can cause false positives for methamphetamine on drug tests. In addition to false-positive results, there are several notable limitations of immunoassay urine screens that can lead to false-negative results.6 Enzyme immunoassays used for amphetamines have low sensitivity to certain drugs commonly used in the rave scene, such as 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxyamphetamine (MDMA), and they are unable to detect phenethylamine-based bath salts. DeGeorge, Jr. M, Weber J. Methamphetamine Urine Toxicology: An In-depth Review. It didn t how much can lifestyle changes lower blood pressure say who the roasted whole sheep belonged to, So Al grabbed this guy, and the final result was very unexpected. 10. The MS confirmation test can come back with 4 possible results: 1) no amphetamines detected; 2) amphetamine only detected; 3) methamphetamine only detected; and 4) both amphetamine and methamphetamine detected (Figure 1). In 1998, the federal government raised the threshold on opiates from 0.3 micrograms to 2 micrograms per milliliter, but some drug testing facilities still go by the old standard. Deerfield, IL: Ovation Pharmaceuticals, Inc.; 2005. October 12, 2022 by World Wide FAQS. Common prescriptions, over the counter medications, herbs, vitamins or even foods can cause you a false positive drug test. The use of cutoff values may be particularly useful in ruling out false-positives due to passive inhalation of substances. 'cross react'), resulting in a 'false positive'. Potential Source of False-Positive. Methamphetamine is illegal except when it is prescribed by a physician for a very limited number of medical conditions. Hair follicle tests can detect drug use for up to 3 months before testing, using hair samples that come from a person's scalp. Some other medications that can cause a false-positive result can be ADHD meds such as Ritalin (methylphenidate), Quinolone antibiotics like Levofloxacin or Ofloxacin, or Metformin . A false positive can potentially lead to a loss of employment, jail time, loss of privileges under probation, revocation of medical license, and exclusion from competitive sports. Often times, drugs that are NOT being tested for can react with the wrong antibody (i.e. Benzodiazepines also are regulary missed on enzyme immunoassay screens. While urine drug tests are most commonly used, their accuracy depends on a number of factors, including the frequency of drug use and the how fast the drug is metabolized by the body.

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